The University of Pennsylvania Prevention Research Center (UPenn PRC) is a community-engaged research center that was founded in 2014. The UPenn PRC’s mission is to improve the health of people in Philadelphia, Southeastern Pennsylvania, and beyond by preventing, reducing, and treating chronic diseases. The center’s primary focus for future years will be on implementation of evidence-based strategies to improve patient and provider communication to optimize clinical and community-based management of cancer in diverse older adults.